Hiro, Baymax, Honey, and Fred are on a stakeout at the San Fransokyo Museum of Art, which is hosting an art party. Fred believes a villain is going to attack the party, and insisted on staking out. While Hiro sees no point in all this, Honey is enjoying herself. She is excited about seeing the Lenore Shimamoto exhibit, which will be displaying her famous master piece, City Rising. According to Honey, the "City Rising" represents the city's rebirth after the great catastrophe of 1906, and up till now it was lost for hundreds of years. Suddenly, there is a panic at the art party when all the guests start running out of the museum. The four heroes go in to check it out, and find Globby. He was trying to commit a heist, but fell through a window. He flees with the "City Rising" painting, and the heroes chase him around the museum. However, they had to be careful not to damage any of the paintings. Honey uses an anti-sticky ball to stop Globby and rescue the painting. Baymax and Hiro apprehend Globby, but he escapes by turning into a bouncy ball.
The next day at San Fransokyo Institute of Technology, Hiro has to send in a school project that he was supposed to work on over the week. The project is to design an alternative solution for a building to withstand the events of an earthquake. Hiro finishes off his model at the last minute, but when Professor Granville tests its performance it immediately breaks up. Karmi also humiliates Hiro when she posts a video of his failure on the web. His friends tell him not to worry so much about failing, but Hiro assures him he is fine and will come up with a better idea for his project. However, all the ideas he comes up with were already done by Go Go, Honey, and Tadashi: magnetic suspension, quick drying foam, and an airbag. Hiro gets frustrated, and eventually runs out of ideas. Despite some encouragement from his friends, Hiro still has nothing for the next presentation. Professor Granville refuses to let himself give up, and insists that he keeps on trying.
Later, Honey brings Baymax back to the San Fransokyo Museum of Art to help him understand the artistic view of art. However, because Baymax is a robot and lacks artistic insight, Honey just ends up confusing him. Meanwhile, Hiro is at home still trying to come up with an idea for his project to no avail. He is still feeling very demoralized. Wasabi and Go Go come over to knock some sense into him, when they receive a call from Honey that Globby trying to steal the "City Rising" again. Hiro, Wasabi, and Go Go arrive at the museum with Fred, Honey, and Baymax's super suits. The museum is on lock down, and Globby is trapped inside. Globby eventually breaks out when Big Hero 6 move in to capture him. He flees with the "City Rising" painting, and the heroes give chase. Globby proves to be more elusive than before, but Big Hero 6 eventually save the painting once again. However, when they try to apprehend him with a freeze ball, Globby suddenly turns into water and escapes into the sewers. Globby escapes to the harbor and discovers that he has the ability to shape shift into anything just by using his thoughts.
Hiro has decided to give up on the earthquake project, much to everyone's disapproval. However, Baymax provides shows him a recording of Tadashi getting frustrated when he failed to get Baymax to work for the fifty-eighth time. In the recording, it shows that Tadashi wanted to give up, much to Hiro's surprise. Just then, Hiro and his friends are informed that Globby is attacking a truck that is transporting the "City Rising" to storage. Using his newfound abilities, Globby finally succeeds in stealing the painting and easily defeats Big Hero 6. Despite their failure to stop Globby, Hiro does not consider this a total loss, because he finally learns that if at first one does not succeed, just try again. With that said, Hiro finally comes up with an idea for his project. His model is fitted with sensors that can send out the exact sonic pulses needed to counteract the seismic forces, saving not just one building but all the others around it. Professor Granville is impressed, and Karmi does not get to catch another moment of failure from Hiro. Instead, Hiro took a picture of her reaction as payback.
- The premiere date for this episode was scheduled for April 5, 2018, but Bob Schooley confirmed that this announcement was not the official US premiere date.
- When Fred tells the art patron that he is an artist, pieces of Fred's hat clip out of it. This was an animation error.
- When Hiro punched Wasabi for no reason, Hiro's cuff turned green for a split second.
- When Go Go, Hiro and Wasabi arrive at the museum, they talk with Honey Lemon and Fred while Baymax stands beside them. The scene switches to Go Go and Hiro for a second, then back to the previous, but now Baymax disappeared.